Animal Models in Obesity

The causes and impacts of obesity are manifold. The genetic analysis in humans is difficult due to the clinical variety, genetic heterogeneity, and the diverse environmental influences. In animal models the genetic heterogeneity and the variety of environmental factors can be minimized.

core unit animal models
Animal models are important in medical research. (Photo: flickr / ErnestFiguras)

This is possible e. g. by specialized breeding (congenic mice). Certain genes can be deactivated (knockout). Genes that are associated with obesity can be detected (candidate genes). The metabolism, adipose tissue and hormones, or the impact of bariatric surgery can be examined in detail, as well as the mechanisms, which protect from obesity and its associated diseases.

Duration: 01.05.2015 – 30.04.2020

Head of Core Unit:

Dr. rer. med. Nora Klöting

Core Unit "Animal Models in Obesity"
Member: student career board
Head of project

+49 341 97-13401

nora [dot] kloeting [at] medizin [dot] uni-leipzig [dot] de