Metabolic effects of vaspin in a transgenic mouse model (Prof. Dr. Peter Kovacs, completed)
The research team of Prof. Kovacs scrutinizes in a transgenic mouse model the effects of vaspin, which is produced in adipose tissue. It is assumed that vaspin increases the cells response to insulin and thus improves sugar metabolism. If the insulin sensitivity of the cells is reduced a type-2-diabetes is the consequence, as is the case in many obese patients.) Vaspin can be detected in various brain regions (hypothalamus, cerebrospinal fluid). The effect of vaspin on adipose tissue, organs, insulin, brain and eating behaviour will be tested in depth not only in different mouse models but also in transgenic mice.
Duration: 01.09.2013 - 30.04.2015
Description of research project