Influence of post-bariatric exercise intervention on epigenetic profile (Prof. Dr. Yvonne Böttcher)

The study examines the influence of a six-month exercise program (endurance and strength training) after bari-atric surgery (Roux-Y-Gastric Bypass) on epigenetic processes in the skeletal muscles, blood and adipose tissue using samples that are taken before and after the exercise program. Epigenetic processes are chemical proce-dures (methylation) on the genomes (DNA) that can be modulated by environmental influences and which affect the gene function. Scientists assume that certain epigenetic influences correlate with adiposity and its ac-companying diseases.

The aim of the study is to investigate genes that are influenced differently by the different exercise programs and which affect body weight and abdominal fat (visceral adipose tissue). The generated data should help to develop recommendations for specific exercise intervention after bariatric surgery in Germany.

Duration: 01.05.2015 – 30.04.2020


Description of research project

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Head of projekt

Prof. Dr. rer. nat. Yvonne Böttcher

Head of research group "Functional genetics of adiposity"
Former member: student career board
Head of project

+49 341 97-15377

yvonne [dot] boettcher [at] medizin [dot] uni-leipzig [dot] de