Impact of bariatric surgery on central serotonin- & norephinephrine transporter availability in obese subjects using Positron Emission Tomography (PET) & selective radio-labelled marker before & 6 months after surgery (Prof. Dr. Hesse, completed)

The study examines the effects of bariatric surgery on the availability of certain messenger substances (neurotransmitter) in the brain that apparently play an important role in adiposity. The distribution of serotonin- and norepinephrin transporter is immediately investigated before the surgical intervention and six months after by means of the Positron Emission Tomography (PET). The results are compared with examinations among slim controls and obese patients which has undergone non- operatively treatment.

This research project has been approved by the Ethics Committee of the Faculty of Medicine of the Universität Leipzig (206-10-b-08032010). The project is recorded in the German Clinical Trial Register (DRKS) with the number DRKS00003571.

Duration: 01.07.2010 - 30.04.2015


Description of research project

text follows

Head of project

Prof. Dr. Swen Hesse

IFB-Professorship "Molecular imaging"
Head of project

+49 341 97-18081

swen [dot] hesse [at] uniklinik-leipzig [dot] de