Imaging brain serotonin transporters as an integrative part of the microbial gut-brain axis and homeostatic control – a feasibility study (Prof. Dr. Swen Hesse, completed)

The gastro-intestinal system and the brain are connected neuronaly. They influence each other and in consequence also the energy balance, mood and thinking. An important role plays the transmitter serotonin. Especially the type of gut microbiome is essential for the communication between gut and brain. This study examines for the first time the coherence between microbiome and a substance which activates serotonin, the serotonin transporter (SERT). Beside the microbiome, certain brain areas and functions and metabolic active hormones are being examined. The aim is to characterize and examine the interactions in obesity.


Duration: 01.11.2013 - 30.04.2015


Description of research project

text follows

Head of project

Prof. Dr. Swen Hesse

IFB-Professorship "Molecular imaging"
Head of project

+49 341 97-18081

swen [dot] hesse [at] uniklinik-leipzig [dot] de