Cholinergic network modulation in disinhibited eating behavior (Prof. Dr. Swen Hesse)

Overweight and obesity are partly due to a lack in regulating one’s eating behavior. This study examines the mechanisms of uncontrolled eating behavior. The neuro-transmitter acetylcholine and further transmitters as well as certain brain regions are crucial for the regulation od appetite and eating. With brain imaging via the combined positron-emission- and magnetic-resonance-tomography these brain regions and transmitters are being examined in study participants – with and without food stimuli. In addition the probands fill out questionnaires with reference to eating behavior. The results of this research could be a first step toward novel pharmaceutical or behavioral treatment approach, which can improve the regulation of eating behavior in obese patients.

Duration: 01.05.2015 – 30.04.2020


Description of research project

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Head of project

Prof. Dr. Swen Hesse

IFB-Professorship "Molecular imaging"
Head of project

+49 341 97-18081

swen [dot] hesse [at] uniklinik-leipzig [dot] de