Role of the thyroid hormonal system in the hypothalamic mediation of food intake and energy homeostasis (Dr. Wiebke Kristin Fenske, completed)
Thyroid hormones (T3/T4) regulate the energy balance / homeostasis of the body. For example, T3 increases the energy consumption and the intake of food. This study examines whether T3 leads to an increased intake of food due to its influence on certain brain regions (hypothalamus) or if this is only a consequence of the higher energy consumption. The effect of T3 is tested in detail in animal models. The animals develop overweight due to excessive eating. The influence of that hormone on the food intake and thus the bodyweight could be a starting point for future adiposity therapies.
Duration: 01.11.2013 - 30.04.2015
Description of research project